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Gamma Irradiation Of Animal Serum

Authors:Armas López Leonel, Piña-Sánchez Patricia, Arrieta Oscar, Guzman de Alba Enrique, Ortiz Quintero Blanca, Santillán Doherty Patricio, Christiani David C., Zúñiga Joaquín and Ávila-Moreno Federico   Abstracts: Several homeobox-related gene (HOX) transcription factors such as mesenchyme HOX-2 (MEOX2) have previously been associated with cancer drug resistance, malignant progression and/or clinical prognostic responses in lung cancer…

Rescue and in vitro characterization of a divergent TBEV‑Eu strain from the Netherlands

Authors: Tabitha E. Hoornweg, Gert‑Jan Godeke, Marieke N. Hoogerwerf, Puck B. van Kasteren, Ankje de Vries, Hein Sprong, Georges M. G. M. Verjans, Debby van Riel , Johan H. J. Reimerink, Barry Rockx & Chantal B. E. M. Reusken   Abstracts: Tick-borne encephalitis virus (TBEV) may cause tick-borne encephalitis (TBE), a potential lifethreatening infection of…

Comparison of HER2-targeted affibody conjugates loaded with auristatinand maytansine-derived drugs

Authors: Wen Yin, Tianqi Xu, Haozhong Ding, Jie Zhang, Vitalina Bodenko, Maria S. Tretyakova c, Mikhail V. Belousov d,e, Yongsheng Liu b, Maryam Oroujeni b, Anna Orlova, Vladimir Tolmachev, Torbjörn Gräslund, Anzhelika Vorobyeva   Abstracts: Treatment with antibody drug conjugates targeting receptors over-expressed on cancer cells is well established for clinical use in several types…

Novel Local “Off-the-Shelf” Immunotherapy for the Treatment of Myeloma Bone Disease

Authors: Sandra Charvátová , Benjamin Motais , Justyna Czapla, Tomasz Cichon, Ryszard Smolarczyk, ZuzanaWalek, Sebastian Giebel, Roman Hájek, and Juli R. Bagó   Abstract: Myeloma bone disease (MBD) is one of the major complications in multiple myeloma (MM)—the second most frequent hematologic malignancy. It is characterized by the formation of bone lesions due to the…

Antitumor activity of the protein kinase inhibitor 1-(β-D-2′-deoxyribofuranosyl)-4,5,6,7- tetrabromo- 1H‑benzimidazole in breast cancer cell lines

Authors and Affiliations : Department of Biomedical Research, National Medicines Institute, Chełmska St. 30/34, 00-725, Warsaw, PolandMirosława KoronkiewiczInstitute of Chemistry, Warsaw University of Life Sciences, Nowoursynowska St. 159C, 02-787, Warsaw, PolandZygmunt Kazimierczuk & Andrzej Orzeszko   Contributions : MK, AO contributed to the study conception. AO and ZK performed synthesis of compound. MK methodology. MK conducted the…

Porcine Serum, Trypsin and other Porcine-Derived Products : Swine Viruses of Importation and Adventitious Concern

Authors: Percy Hawkes   The rapid and seemingly uncontrolled spread of African swine fever (ASF) throughout China and many of its neighboring countries within the last 19 months (August 2018-March 2020) has put the rest of the world on high alert. The geographic distribution of viruses of importation concern, like ASF virus (ASFV), can change…

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